Case Study  ·  Biomarker Landscape

Choosing biomarkers for IL-17 trials.

A biotech with a best-in-class IL-17 inhibitor needed biomarkers to track disease progression in its trials. We combined trial data, literature, AI-driven analysis and expert interviews to identify 153 biomarkers and recommend panels for each indication.

The Client

The client is a biotech company developing a best-in-class IL-17 inhibitor for autoimmune conditions. It wanted to choose biomarkers that would strengthen its clinical trials.

The Challenge

Four indications.
Pick the right markers.

Prescouter was asked to identify biomarkers for monitoring disease progression in IL-17 inhibitor trials across psoriatic arthritis, uveitis, hidradenitis suppurativa and enthesitis, as late-stage demands keep rising.

  • Indications

    Four autoimmune targets

    Arthritis, uveitis, skin and enthesitis.

  • Evidence

    Established and emerging

    Covering proven and novel markers.

  • Practicality

    Panels and matrices

    Which samples and tests to use.

Our Approach

Building a biomarker landscape from four sources.

Trial analysis
4indications covered

Mine the trials

We analyzed clinical trial data with AI-driven tools across all four indications of interest.

Literature review
153biomarkers identified

Map the evidence

We reviewed the literature to capture both established and emerging biomarkers in each domain.

Expert interviews
Vettedreadiness insights

Test the readiness

Experts weighed in on readiness, reliability and expected challenges for each biomarker.

The Outcome

Biomarker panels ready for the clinic.

Prescouter identified 153 biomarkers across all areas of interest and recommended biomarker panels, sample matrices and testing methods for each domain. Expert insights on readiness, reliability and challenges gave the client a clear view of how ready biomarkers are for its trials.

  • Landscape

    153 biomarkers

    Established and emerging, in four indications.

  • Panels

    Per-indication recommendations

    Panels, sample matrices and test methods.

  • Readiness

    Expert-vetted insight

    Reliability and challenges for each option.

Late-stage trials ask more of biomarkers than ever. Choosing them early, with evidence and expert input, keeps a program on track.

Let’s Talk

Which biomarkers could strengthen your trials?

Map the evidence, test it with experts and build panels that fit each indication. Wherever you’re starting from, we’ll help you get there.

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