Case Study · Technology Scouting

Looking beyond silicone in prefilled syringes.

A global medical technology company wanted alternatives to the silicone coating used in syringe barrels, to improve drug stability in prefilled systems. We profiled eight coating classes and identified three as the most promising.

The Client

The client is a global medical technology company. It engaged Prescouter to find the most promising alternatives to silicone coatings, in both R&D and commercial stages.

The Challenge

Protect the drug.
Replace the standard.

Silicone is the standard coating for syringe barrels, but it can affect drug stability in prefilled systems. Prescouter was asked to assess which alternative coatings could work, and what it would take to adopt them.

  • Readiness

    Technology maturity

    Where each coating stands for use in syringe applications.

  • Integration

    Manufacturing needs

    The process changes needed to apply each coating at scale.

  • Regulation

    Approval considerations

    Regulatory factors that shape how quickly a coating can be adopted.

Our Approach

Scouting coatings through research and expert input.

Technology scan
70+coating technologies

Scan the field

We identified more than 70 coating technologies, 30 commercial and 42 still in research.

Coating classes
8classes profiled

Compare on what matters

Eight coating classes were profiled on the parameters and performance features that matter for syringe use.

Expert interviews
4expert interviews

Check with specialists

Specialists in healthcare coating technology and intellectual property validated the findings.

The Outcome

Three alternatives worth pursuing.

Prescouter gave the client a detailed view of viable alternatives to silicone, covering technology readiness for syringes, integration challenges and regulatory considerations, with a deep dive into the three most promising coating classes and their manufacturing requirements.

  • Shortlist

    3 priority coating classes

    The most promising alternatives to silicone, examined in depth.

  • Pipeline

    30 commercial, 42 in research

    A full view of what is available now and what is coming.

  • Execution

    Manufacturing requirements

    What each option needs to move into production.

Replacing an industry standard starts with knowing exactly what each alternative will demand of your process.

Let’s Talk

What could replace your current standard?

Find and assess the technologies that could improve your product's performance. Wherever you're starting from, we'll help you get there.

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