Case Study · Technology Assessment

Raising the viral titer of bioreactors for gene therapy.

A global biotechnology company wanted to know which new technologies could lift viral titer in its bioreactors, and whether to license, buy or build them. We compared the options and helped the client set realistic expectations.

The Client

The client is a global biotechnology company looking to improve viral production in bioreactor systems for gene therapy. It engaged Prescouter through a Research Support Service project to find hard numbers on new technologies and decide whether to license or acquire a solution, or develop one in house.

The Challenge

Map the options.
Put numbers on each one.

Prescouter was asked to map the technologies that could raise virus production in bioreactors, compare them with real data, and recommend how to proceed.

  • What exists

    New and upcoming technologies

    Technologies that could raise virus production levels in bioreactors.

  • How they compare

    Quantitative data and IP

    Data and patents for each technology, used to rank them from most to least promising.

  • What to do

    Strategic recommendations

    How to acquire or implement the most promising technologies.

Our Approach

Testing a working hypothesis with research and experts.

Secondary research
Scantechnology options

Understand the field

We used secondary research to understand the field and profile technical approaches that could deliver much higher viral titer.

Client review
Reviewan initial hypothesis

Agree the direction

An initial hypothesis was reviewed with the client team before going further.

Expert interviews
Verifywith field experts

Check with experts

We then tested the hypothesis through a series of interviews with subject matter experts.

The Outcome

Realistic gains, backed by a working model.

Prescouter built a preliminary ROI model and advised the client on the level of improvement it could reasonably expect from each approach. The client built this analysis into its business development process.

  • Returns

    A preliminary ROI model

    A model of the returns the client could expect from each approach.

  • Expectations

    What improvement to expect

    A realistic view of the titer gains each approach could deliver.

  • Strategy

    License, acquire or build

    Guidance on how to acquire or implement the most promising technologies.

Big claims about viral yield are easy to find. Knowing what improvement you can actually expect, and what it is worth, is what moves a decision.

Let’s Talk

Where could your process gain the most yield?

Build your bioprocess plans on a clear view of the technologies, the data, and the returns. Wherever you’re starting from, we’ll help you get there.

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